Age-related macular degeneration can lead to profound central visual loss.

Differential diagnosis

Genetic macular diseases such as Sorsby dystrophy and Stargardt disease.

Consider also Intraretinal processes such
as intraretinal lipid (exudates), retinal emboli and cotton-wool spots (infarcts).


See management under AMD – dry and AMD – exudative

Fig. 5.1

Flow chart showing development of age-related
macular degeneration (AMD). ARM, age-related maculopathy. Definitions are
consistent with those used in the Age-Related Eye Disease Study (AREDS).

Age-related macular degeneration – classification